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Results for "

Munc13-1 translocation

" in MedChemExpress (MCE) Product Catalog:

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Natural
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-105231
    Bryostatin 1
    1 Publications Verification

    		 PKC HIV Bacterial Infection Neurological Disease Inflammation/Immunology Cancer
    Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties .
    Bryostatin 1
  • HY-149490
    AJH-836

    		PKC Neurological Disease
    AJH-836 is an activator of Munc13-1 and PKC ε/α (Kd: 4.5 nM for PKCα) . AJH-836 triggers the translocation of Munc13-1 from the cytoplasm to the plasma membrane. AJH-836 can be used for research of neurodegenerative diseases .
    AJH-836

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